The Proteinuria/Creatininuria ratio is a medical calculation used to assess the amount of protein being excreted in the urine compared to the level of creatinine. This ratio provides a standardized way to evaluate kidney function and detect potential kidney damage or disease. It is commonly measured using a random (spot) urine sample, which makes it a convenient alternative to 24-hour urine collection.
Under normal conditions, healthy kidneys prevent significant amounts of protein from leaking into the urine. However, when the kidneys are damaged, especially in conditions like chronic kidney disease (CKD), diabetes, or hypertension, they may allow proteins—mainly albumin—to pass into the urine. This abnormal presence of protein in urine is called proteinuria, and it's an important indicator of kidney stress or damage.
Simply measuring the amount of protein in a urine sample is not always accurate, because the concentration of urine can vary depending on hydration levels and the time of day. To account for this, healthcare providers compare the amount of protein to the amount of creatinine, a waste product that the body produces at a relatively constant rate. This comparison allows for a more reliable result that reflects the true level of protein excretion.
The Proteinuria/Creatininuria ratio is usually expressed as mg of protein per mmol or per gram of creatinine. Two common formats include:
This ratio helps identify whether a patient has normal protein levels or if they fall into a range that suggests mild, moderate, or severe proteinuria. For example:
You should use the Proteinuria/Creatininuria Ratio Calculator whenever you need to evaluate or monitor the amount of protein in your urine relative to creatinine. This is especially useful in medical situations where kidney function is in question, or when tracking a known condition over time.
Here are some common scenarios when this calculator is helpful:
This calculator is most useful when you already have test results for both protein and creatinine levels in your urine. If you're unsure about your values or units, it's best to consult with a healthcare professional before interpreting the results.
The Proteinuria/Creatininuria Ratio Calculator is designed to be simple and user-friendly. Follow these steps to get accurate results based on your urine test values.
mg/l, g/dl, g/l, and µmol/l.
mmol/l, µmol/l, mg/l, or mg/dl.
The results will appear in the boxes labeled "Ratio : ___ mg/mmol" and "Ratio : ___ mg/g". These ratios help your doctor assess whether your protein levels in urine are within a healthy range.
Tip: Double-check that the units selected match the ones on your lab report. Using incorrect units may lead to misleading results.
Proteinuria refers to the presence of excess protein in the urine. In healthy individuals, only a very small amount of protein is filtered into the urine by the kidneys. When the kidneys are damaged or under stress, they may allow larger amounts of protein to pass through, which can be a sign of kidney disease or other underlying health conditions.
Protein levels in urine are usually measured through a urine test, and the results can be expressed in different units depending on the laboratory:
In the calculator, simply enter the numeric value shown on your lab report and select the corresponding unit from the dropdown menu.
Creatininuria is the concentration of creatinine in the urine. Creatinine is a waste product that comes from the normal breakdown of muscle tissue. The amount of creatinine in the urine tends to remain stable throughout the day, making it an excellent reference for comparing against other substances, such as protein.
Measuring creatininuria allows us to correct for variations in urine concentration and improves the accuracy of protein measurements. Common units for creatinine in urine include:
As with proteinuria, enter the creatinine value from your lab report and select the correct unit.
Selecting the correct unit is very important to ensure the calculator gives accurate results. Always refer to your urine test report and look for the unit printed next to the value. Make sure you match it exactly in the calculator’s dropdown menus.
For example:
Using the wrong unit can lead to incorrect results and misinterpretation. If you're not sure which unit to select, ask your healthcare provider or laboratory for clarification.
The mg/mmol result shows how many milligrams of protein are present in your urine for every millimole of creatinine. This unit is commonly used in medical guidelines and is especially useful in tracking kidney function over time.
Because creatinine levels tend to remain stable throughout the day, comparing protein to creatinine in this way helps remove the effect of urine concentration. A higher mg/mmol ratio indicates more protein is being lost in the urine, which can suggest kidney stress or damage.
The mg/g result shows how many milligrams of protein are present for each gram of creatinine. This unit is more common in the United States and is widely used in guidelines from American medical organizations.
Just like the mg/mmol ratio, a higher mg/g value means more protein loss. Doctors may use either unit depending on local standards or personal preference, but both are used to assess the same thing: how much protein is in the urine compared to creatinine.
Understanding your result depends on comparing it to accepted reference ranges. Below are general guidelines used by healthcare professionals:
| Protein/Creatinine Ratio | mg/mmol | mg/g | Interpretation |
|---|---|---|---|
| Normal | Less than 15 | Less than 150 | No significant proteinuria |
| Moderately increased | 15 – 50 | 150 – 500 | May indicate early kidney disease or mild damage |
| Severely increased | Over 50 | Over 500 | Sign of significant kidney damage or disease |
Keep in mind that these ranges are general guidelines. Your healthcare provider may interpret your results differently depending on your age, health condition, and other test results. Always discuss your results with a medical professional for an accurate diagnosis.
This ratio helps evaluate how much protein is being lost in the urine, which can be a sign of kidney damage or disease. It is especially useful for diagnosing and monitoring conditions like chronic kidney disease, diabetes, and high blood pressure.
No, this calculator works with a single (spot) urine sample. Because creatinine is excreted at a relatively constant rate, the ratio provides reliable results without needing a full-day urine collection.
The units are usually printed next to the values on your lab report. If you're unsure, contact your healthcare provider or laboratory before using the calculator. Choosing the wrong unit can lead to inaccurate results.
A ratio over 50 mg/mmol (or 500 mg/g) usually indicates a high level of protein in the urine and may suggest significant kidney damage. However, any abnormal result should be reviewed by a healthcare professional.
Yes. Exercise, fever, stress, and dehydration can cause a temporary increase in protein levels. That’s why a doctor may recommend repeating the test if the result is borderline or abnormal.
It can be used, but reference ranges and interpretations may differ in children and during pregnancy. For example, proteinuria during pregnancy may indicate a condition like preeclampsia. Always consult a doctor for age- or condition-specific guidance.
This calculator is intended for educational and informational purposes only. It should not replace professional medical advice, diagnosis, or treatment. Always consult a healthcare provider to interpret your results accurately.
If your protein/creatinine ratio is above the normal range, speak with your doctor. They may recommend further testing, lifestyle changes, or treatment depending on the underlying cause.
The Proteinuria/Creatininuria Ratio Calculator is provided for informational and educational purposes only. It is not intended to replace professional medical advice, diagnosis, or treatment.
Always consult a qualified healthcare provider or medical professional if you have any questions about your health, your lab results, or the interpretation of your protein/creatinine ratio.
The accuracy of the calculator depends on the correctness of the input values and the selected units. Using incorrect units or values may lead to misleading results. This tool does not store or share any personal health information.
By using this calculator, you agree that the creators and publishers of this tool are not responsible for any outcomes, medical decisions, or actions taken based on the results provided. For any medical concerns, please consult your doctor.